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tag faculty culture disease medicine
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD
| Mar 15, 2024
| 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Viral Protein Behind Chronic Inflammation in People with HIV: Study
Natalia Mesa, PhD
| Dec 12, 2022
| 3 min read
The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice.
Pancreatic Organoids Take the Stage
Laura Tran, PhD
| Dec 1, 2023
| 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
Top 7 in medicine
Megan Scudellari
| Jan 30, 2011
| 4 min read
A snapshot of the most highly ranked articles in medicine and related areas, from Faculty of 1000
Unbalanced Allele Expression Associated with Mutation, Disease
Natalia Mesa, PhD
| Feb 2, 2023
| 5 min read
A study identifies nearly 3,000 genes where one allele tends to be expressed more than the other, but the findings ignited controversy in the field.
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines
Katherine Irving
| Jan 20, 2023
| 4 min read
A method for culturing the infectious stage of the
Plasmodium
lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.
Is Medicine Ready for Clinical CRISPR?
John Parrington
| Dec 1, 2016
| 3 min read
Using precision genome editing to treat or prevent human disease may require several leaps of faith.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD
| Sep 8, 2023
| 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Short-lived Molecules Support Long-term Memory
Alejandra Manjarrez, PhD
| Jun 6, 2023
| 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
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