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tag lc ms evolution disease medicine

On the iTRAQ
Emma Hitt | Sep 26, 2004 | 1 min read
Applied Biosystems www.appliedbiosystems.com, based in Foster City, Calif., has introduced a new family of reagents for multiplexed LC/MS experiments. The iTRAQ reagents enable comparison of protein expression in multiple samples, such as those of normal, diseased, and drug-treated states, and have the ability to detect posttranslational modifications, the company claims. The company has also released Pro QUANT software for automated analysis of LC/MS data collected using the reagents.ICAT reage
Whole-Genome SNP Genotyping
Marilee Ogren | Jun 1, 2003 | 8 min read
Clockwise from top left: images courtesy of Affymetrix, Illumina, Sequenom and Illumina Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease susceptibility, environmental response, and drug metabolism. Researchers are understandably keen to dissect these variations, most of which take the form of single-nucleotide polymorphisms (SNPs). A SNP (pron
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
Soybeans Hit Main Street
Barry Palevitz | Mar 19, 2000 | 8 min read
Once a favorite of Chinese emperors, tofu is now big time. From supermarkets to health food boutiques, diet-conscious Americans are buying soybeans, not just as tofu but in infant formula, soy milk, and soy burgers. Soy even has the Food and Drug Administration's seal of approval. Last October the FDA responded to a petition by Protein Technologies International, a St. Louis-based DuPont company specializing in soy products, by authorizing claims that soy protein is good for the heart. Acc

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