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Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Sequencing Genomes in the ICU Improves Outcomes

Sequencing Genomes in the ICU Improves Outcomes

By | October 19, 2017

A handful of infants in a neonatal intensive care unit who were diagnosed with rare diseases using whole-genome sequencing had shorter hospital stays and better health outcomes, researchers find.

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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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image: Compound Found in Red Wine Boosts Immune Cell Function

Compound Found in Red Wine Boosts Immune Cell Function

By | October 17, 2017

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 

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image: Cancers Relapse by Feeding Off Immune Signals

Cancers Relapse by Feeding Off Immune Signals

By | October 16, 2017

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

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image: Damage Patroller

Damage Patroller

By | October 1, 2017

Stephen Elledge has built a career studying how eukaryotic cells maintain genomic integrity.

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The 38-year-old synthetic biologist comes from a long line of tinkerers and engineers.

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image: Live Cell Extractions

Live Cell Extractions

By | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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  3. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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    Features Running on Empty

    Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.

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