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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By Amanda B. Keener | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Sequencing Genomes in the ICU Improves Outcomes

Sequencing Genomes in the ICU Improves Outcomes

By Bob Grant | October 19, 2017

A handful of infants in a neonatal intensive care unit who were diagnosed with rare diseases using whole-genome sequencing had shorter hospital stays and better health outcomes, researchers find.

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image: Damage Patroller

Damage Patroller

By Anna Azvolinsky | October 1, 2017

Stephen Elledge has built a career studying how eukaryotic cells maintain genomic integrity.

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The 38-year-old synthetic biologist comes from a long line of tinkerers and engineers.

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image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By Shawna Williams | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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Pauses may help cells fine-tune gene expression.

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image: Infographic: Macrophages Around the Body

Infographic: Macrophages Around the Body

By Claire Asher | October 1, 2017

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

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