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Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies

Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.

Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.

obesity, disease & medicine

brown fat, metabolism, cardiovascular disease, cardiometabolic disease, genetics & genomics, immunology, Q&A, adipose tissue, obesity
Q&A: Brown Fat Linked to Better Cardio and Metabolic Health
Amanda Heidt | Jan 12, 2021 | 5 min read
Paul Cohen of the Rockefeller University describes his study of thousands of people, finding that the energy-burning tissue is tied to a lower risk of for several diseases, including type 2 diabetes, high blood pressure, and heart disease.
Nearly All NYC-Area COVID-19 Hospitalizations Had Comorbidities
Lisa Winter | Apr 24, 2020 | 2 min read
The most common preexisting conditions among the patients were diabetes, obesity, and hypertension.
70 years of disease research graphic
Image of the Day: 70 Years of Disease Research
Amy Schleunes | Jan 21, 2020 | 1 min read
A video chronicles the course of disease research and prompts questions about where scientists may focus their studies in the future.
Exercise Changes Our Gut Microbes, But How Isn’t Yet Clear
Ashley Yeager | Aug 15, 2019 | 5 min read
Physical activity, independent of diet, shifts the composition of bacteria in the intestines, spurring researchers to search for species that might provide benefits akin to working out.
scientist to watch laura bowers
Laura Bowers Works to Sever the Link Between Obesity and Cancer
Shawna Williams | Jul 15, 2019 | 3 min read
The Purdue University nutrition researcher delves into the details of how fat tissue affects tumors.
Microbe Miner: A Profile of Rob Knight
Anna Azvolinsky | Jun 1, 2019 | 9 min read
Developing computational tools to analyze the reams of microbial sequencing data his lab generates, the UC San Diego microbiologist is a pioneer of microbiome research.
Fat Tissue Can Help Cancer Cells Proliferate, Metastasize
Catherine Offord | Apr 1, 2019 | 3 min read
Researchers disentangle how adipocytes communicate with prostate tumors in mice.
Self-Control Center in the Brain Linked to Weight Loss
Ashley P. Taylor | Oct 18, 2018 | 2 min read
Activity in the lateral prefrontal cortex was the best correlate of weight loss in a study of people on a restricted-calorie diet.
Maternal Obesity and Diabetes Linked to Autism in Children
Sukanya Charuchandra | Oct 1, 2018 | 5 min read
Inflammation may be a strong contender for the connection between mom’s weight and children’s neurodevelopment, according to lab studies on animals.
Researchers Identify Biomarkers for Obesity Risk in Women
Catherine Offord | May 31, 2018 | 2 min read
Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.
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