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tag polar genetics genomics

Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Red blood vessels that decrease in diameter as they radiate outward are pictured on a pink and white surface
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena, PhD | Aug 18, 2021 | 3 min read
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
A Fierce Competitor
Karen Hopkin | Apr 1, 2008 | 7 min read
Christine Jacobs-Wagner's studies of a bacterial species have changed how scientists think about cell shape and polarity.
Preimplantation Genetic Diagnosis: The Next Big Thing?
Ricki Lewis | Nov 12, 2000 | 9 min read
Courtesy of David Hill, ART Reproductive Center Inc.Two separated blastomeres subjected to FISH analysis to check the chromosomes. In early October, preimplantation genetic diagnosis (PGD) made headlines when a Colorado couple used assisted reproductive technology (ART) to have a baby named Adam, whose umbilical cord stem cells could cure his six-year-old sister Molly's Fanconi anemia.1 When Adam Nash was a ball of blastomere cells, researchers at the Reproductive Genetics Institute at Illinois
Reductio Ad Amino Acid
Bob Sinclair | Feb 1, 1999 | 10+ min read
Date: February 1, 1999Fusion/Tag Proteases TableProteolytic Enzymes TableTable 3Table 4 A proteome analysis aims to characterize all proteins expressed by an organism or tissue. The next step will be to correlate a protein profile with the appropriate genome, and beyond that researchers will want to understand the correlations between levels of proteins, co- and post-translational modifications, and cell or tissue activity. Many of the technologies that are necessary to realize this goal are de
New Technologies Shed Light on Caveolae
Ben Nichols | Jun 1, 2018 | 10+ min read
The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.
Week in Review: April 7–11
Tracy Vence | Apr 11, 2014 | 3 min read
Stress and telomere length in children; osmotic channel protein identified; amoeba nibbles, then kills cells; amphetamine and mental disorder risk; news from AACR
The Gates of Immortality
Yves Barral | Oct 1, 2010 | 10+ min read
By Yves Barral The Gates of Immortality Did biology evolve a way to protect offspring from the ravages of aging by creating a physical barrier that separates the parent from its young? Dr. Stanley Flegler, Visuals Unlimited he idea that every organism must age was a concept that surprised many biologists. For a long time, aging was thought to be a process occurring only in multicellular organisms. The reason for this arguably odd presumption was that we knew so
Lipids in the Spotlight
Carina Storrs | Aug 1, 2012 | 8 min read
A guide to studying lipids using mass spectrometry

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