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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Bees’ Molecular Responses to Neonicotinoids Determined
Catherine Offord | Mar 22, 2018 | 4 min read
Researchers pinpoint a protein that can metabolize at least one of the insecticides, highlighting a route to identifying compounds that are friendlier to the critical pollinators.
Tagged for Cleansing
Michele Pagano | Jun 1, 2009 | 10+ min read
Tagged for Cleansing Not just the cell's trash and recycling center, the ubiquitin system controls complex cellular pathways with elegant simplicity and precision. By Michele Pagano have always gravitated toward order. I may even take it a bit too far according to friends who liken my office to a museum. However, I like to think it not a compulsion, but a Feng Shui approach to life. With this need for order, I may have been better suited to
Eytan Stibbe wears a headset and a blue shirt while surrounded by computers and other equipment on the International Space Station.
Whenever, Wherever: Taking DNA Amplification Outside the Lab
Hannah Thomasy, PhD | Dec 4, 2023 | 10 min read
Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.
Insulin Receptor Takes Center Stage
Jeffrey Perkel | Sep 2, 2001 | 6 min read
The defining characteristic of diabetes is its failure to properly maintain blood glucose levels. Normally, the elevated glucose concentration that occurs after eating induces the release of the hormone insulin from pancreatic beta cells. Cells expressing the insulin receptor can bind insulin and respond to the signal, thereby maintaining glucose homeostasis through changes in gene expression patterns and cellular metabolism. Insulin-induced effects include enhanced glucose uptake and glycogen s
Biology’s New Supermodel
Megan Scudellari | Jul 20, 2011 | 5 min read
Induced pluripotent stem cells are biology’s hottest new tool for understanding human disease.
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
How Bulgy Bears Keep Diabetes at Bay
Jyoti Madhusoodanan | Aug 7, 2014 | 1 min read
A genetic switch in hibernating bears keeps the animals from becoming insulin-resistant. 
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

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