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tag induced ovulation developmental biology immunology

The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
Master of the Cell
Judy Lieberman | Apr 1, 2010 | 10+ min read
By Judy Lieberman Master of the Cell RNA interference, with its powerful promise of therapy for many diseases, may also act as a master regulator of most—if not all—cellular processes. RNA silencing. Computer artwork showing a length of RNA (yellow with red rings) bound to an RNA-induced silencing complex (RISC). © Medi-Mation Ltd / Photo Researchers, Inc. ne of the biggest surprises in biology in the past d
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Roll-Your-Own Microarrays
Jim Kling | Jan 6, 2002 | 3 min read
CDNA microarrays hold great promise for characterizing disease and performing genetic studies, but they're not exactly an out-of-the-box technology just yet. Often the scientists must prepare their own chips. Yet, this process is limited by the amount of space on the array itself—forcing researchers to make choices about which genes to include in their sample. Clinical microarray applications are further limited by the availability of sufficient cell numbers for testing purposes. Illumina
Notable
Jeffrey Perkel | Jan 6, 2002 | 4 min read
J.A. Camarero et al., "Peptide chemical ligation inside living cells: In vivo generation of a circular protein domain," Bioorganic and Medicinal Chemistry, 9[9]:2479-84, September 2001. F1000 Rating: Recommended "To investigate whether chemo-selective peptide ligations work in vivo, the authors demonstrate the in vivo head-to-tail cyclization of a bioactive SH3 domain using native chemical ligation. The protein precursor was constructed using a clever combination of an intein-fusion protein an
Antibodies Making Their Way From The Clinic To The Research Lab
Holly Ahern | Sep 17, 1995 | 10 min read
if (n == null) The Scientist - The Immune Response The Scientist 9[18]:18, Sep. 18, 1995 Tools The Immune Response By Holly Ahern Imagine that you've just cloned a gene for a bacterial enzyme with unique structural properties and you want to find out more about it. What natural role does the enzyme play, you wonder, and do organisms other than bacteria produce it? To answer these questions, you could screen countless genomic libraries for clones bearing si
Distinguishing Th1 and Th2 Cells
Jeffrey Perkel | May 13, 2001 | 10+ min read
Reagents That Distinguish Th1 and Th2 cells Courtesy of R&D SystemsSchematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells. Editor's note: Although individual techniques are associated with specific researchers in this article, it should be noted that these investigators commonly use several different techniques to analyze T lymphocyte populations. The human body is constantly under siege. It must defend itself fr

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