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image: Valerie Horsley Gets Under Skin

Valerie Horsley Gets Under Skin

By | May 1, 2017

The Yale University cell and molecular biologist is probing the deep mysteries of epidermal cells.

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image: Infographic: How the Zebrafish Got Its Stripes

Infographic: How the Zebrafish Got Its Stripes

By | May 1, 2017

Immune cells called macrophages shuttle cellular messages in the skin.

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image: Infographic: Proteasome Basics

Infographic: Proteasome Basics

By | May 1, 2017

The structure and function of the cell's protein-degrading machine

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image: Viral Trigger for Celiac Disease?

Viral Trigger for Celiac Disease?

By | April 6, 2017

A common, seemingly benign human virus can trigger an immune response that leads to celiac disease in a mouse model, researchers show. 

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Mice engineered to overproduce the organelles involved in cell division spontaneously develop malignancies.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Starvation Response Triggers Melanoma Invasion

Starvation Response Triggers Melanoma Invasion

By | April 1, 2017

Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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