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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: The Rising Research Profile of 23andMe

The Rising Research Profile of 23andMe

By | December 1, 2017

An exploration of the genetics of earlobe attachment is just the latest collaborative research project to come out of the personal genetic testing company.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Six-Letter DNA Alphabet Produces Proteins in Cells

Six-Letter DNA Alphabet Produces Proteins in Cells

By | November 29, 2017

Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.

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image: European Research Council Founder, Molecular Biologist Dies

European Research Council Founder, Molecular Biologist Dies

By | November 20, 2017

Fotis Kafatos, a Greek researcher famous for his work on malaria, has died at age 77.

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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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image: Cancer Researcher, Former AACR President Dies

Cancer Researcher, Former AACR President Dies

By | November 13, 2017

Donald Coffey, a longtime professor at Johns Hopkins University, discovered the nuclear matrix within cells and its role in DNA replication.

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Single-cell analyses from mouse samples detail the changes in cell distribution during infections.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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    Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

  2. That Other CRISPR Patent Dispute
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    The Broad Institute and Rockefeller University disagree over which scientists should be named as inventors on certain patents involving the gene-editing technology.

  3. EPO Revokes Broad’s CRISPR Patent
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    Shortly after ruling out the earliest priority dates on a foundational patent for CRISPR gene-editing technology, the European Patent Office rescinded the patent entirely—and more are likely to follow.

  4. Learning Opens the Genome
    Daily News Learning Opens the Genome

    Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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