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tag france disease medicine evolution

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Directed Evolution, Phage Display Nab Chemistry Nobel
Catherine Offord and Kerry Grens | Oct 3, 2018 | 4 min read
The 2018 award goes to Frances Arnold, Gregory Winter, and George Smith.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Evolution, Resisted
Elie Dolgin | Oct 1, 2009 | 10+ min read
Scientists are trying to design the last malaria control agent the world will ever need.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Illustration of bacteriophages infecting a bacterium
Phages Treat Gut Inflammation in Mice
Andy Carstens | Aug 4, 2022 | 5 min read
Mixtures of viruses that attack inflammatory bowel disease–causing bacteria in mice also survive the digestive tract and are well-tolerated in humans, a study finds.
Illustration of viruses represented with different colors overlapping each other.
What Happens When You Catch More than One Virus?
Alejandra Manjarrez, PhD | Dec 7, 2022 | 8 min read
The “tripledemic” shines a spotlight on viral interference, in which one infection can block another.
Can Destroying Senescent Cells Treat Age-Related Disease?
Katarina Zimmer | Mar 1, 2020 | 10+ min read
A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.
Novartis’s $9.7 Billion Purchase Includes Novel PCSK9 Inhibitor
Emily Makowski | Nov 25, 2019 | 2 min read
The pharmaceutical firm is buying The Medicines Company, which recently devoted its efforts into developing the cholesterol-lowering medication.

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