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image: Cancer Immunotherapist

Cancer Immunotherapist

By Jef Akst | April 1, 2015

Scientist to Watch Yvonne Saenger explains recent advances in using biomarkers to identify cancer patients who might benefit most from immunotherapy.

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image: Cancer Kismet

Cancer Kismet

By Jenny Rood | April 1, 2015

Fate mapping allows researchers to follow cancer progression from its cell type of origin.

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By Haroldo Silva, David Halvorsen, and Jeremy D. Henson | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: Getting Your Sugar Fix

Getting Your Sugar Fix

By Kate Yandell | April 1, 2015

A guide to glycan microarrays

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image: Manipulative Microbiomes

Manipulative Microbiomes

By Jenny Rood | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

3 Comments

image: Setbacks and Great Leaps

Setbacks and Great Leaps

By Sue Armstrong | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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Signaling Resistance

By Jenny Rood | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: Toggling Between Life and Death

Toggling Between Life and Death

By Ashley P. Taylor | April 1, 2015

In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.

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image: Yvonne Saenger: Immunotherapy Pioneer

Yvonne Saenger: Immunotherapy Pioneer

By Jef Akst | April 1, 2015

Assistant Professor, Department of Medicine, Columbia University. Age: 41

5 Comments

image: From Many, One

From Many, One

By Elena E. Giorgi | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

4 Comments

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