Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.
The Scientist Marketing Team | Sep 26, 2013 | 3 min read
The Scientist brings together a panel of experts who parse the hope and hype in an effort to educate the audience about the successes and caveats of using iPSCs.
The Scientist Creative Services Team in collaboration with MilliporeSigma | Mar 29, 2021 | 3 min read
A new specialized cell culture media system generates induced pluripotent stem cell-derived lung organoids that more closely resemble the diversity of cell types found in the human lung.
A 3D variation of pooled CRISPR screens could connect the dots between autism spectrum disorder genetics and cell fate pathways in the developing brain.
Researchers are developing ways to convert mature somatic cells from one cell type to another, avoiding the tumor-causing pluripotent stage associated with stem cells.