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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By Ruth Williams | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Infographic: Combo Method of Stem Cell Generation

Infographic: Combo Method of Stem Cell Generation

By Ruth Williams | December 1, 2017

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Image of the Day: Skate Youngsters 

Image of the Day: Skate Youngsters 

By The Scientist Staff | November 28, 2017

Scientists study the development of scales in skate embryos. 

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image: European Research Council Founder, Molecular Biologist Dies

European Research Council Founder, Molecular Biologist Dies

By Catherine Offord | November 20, 2017

Fotis Kafatos, a Greek researcher famous for his work on malaria, has died at age 77.

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image: Cancer Researcher, Former AACR President Dies

Cancer Researcher, Former AACR President Dies

By Kerry Grens | November 13, 2017

Donald Coffey, a longtime professor at Johns Hopkins University, discovered the nuclear matrix within cells and its role in DNA replication.

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Single-cell analyses from mouse samples detail the changes in cell distribution during infections.

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Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.

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