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tag fluorescent labels immunology ecology culture

Flow Cytometry for the Masses
Richard P. Grant | Dec 1, 2011 | 2 min read
Tagging antibodies with rare earth metals instead of fluorescent molecules turns a veteran technique into a high-throughput powerhouse.
A section of a mouse distal colon showing luminal contents with bacteria in magenta, the mucus lining (green) and the epithelial cell barrier of the gut (blue, right).
Mapping the Neighborhoods of the Gut Microbiome
Abby Olena, PhD | Jul 1, 2022 | 7 min read
Researchers are going beyond fecal samples to understand how the patterns of commensal microbes in the gastrointestinal tract influence development and health.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
Suited to a T
Kelly Rae Chi | May 1, 2013 | 8 min read
Sorting out T-cell functional and phenotypic heterogeneity depends on studying single cells.
Rethinking Lymphatic Development
Amanda B. Keener | Aug 1, 2015 | 9 min read
Four studies identify alternative origins for cells of the developing lymphatic system, challenging the long-standing view that they all come from veins.
The Jon Yewdell Selection
Jon Yewdell | Apr 6, 2003 | 3 min read
My Top 5 | The Jon Yewdell Selection Courtesy of Jon Yewdell 1. In the now distant year of 1970, the physical nature of the plasma membrane (or any membrane for that matter) was uncertain. Frye and Edidin used Sendai virus to fuse human and mouse cell, then stained the cells with fluorochrome-labeled antibodies specific for human or mouse antigens.1 They watched the unfolding drama in a fluorescent microscope as the human and mouse proteins completely mixed in real time, providing an elega
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Flow Cytometry On-a-Chip
Jeffrey M. Perkel | Jun 1, 2015 | 7 min read
Novel microfluidic devices give researchers new ways to count and sort single cells.
Macro, Mini, Micro
Carina Storrs | Jan 1, 2013 | 7 min read
Clever microfluidic platforms take the study of protein-protein interactions to a new level.
Antibodies Making Their Way From The Clinic To The Research Lab
Holly Ahern | Sep 17, 1995 | 10 min read
if (n == null) The Scientist - The Immune Response The Scientist 9[18]:18, Sep. 18, 1995 Tools The Immune Response By Holly Ahern Imagine that you've just cloned a gene for a bacterial enzyme with unique structural properties and you want to find out more about it. What natural role does the enzyme play, you wonder, and do organisms other than bacteria produce it? To answer these questions, you could screen countless genomic libraries for clones bearing si

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