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image: Primary Cilia in Neurons Linked to Obesity

Primary Cilia in Neurons Linked to Obesity

By Abby Olena | January 8, 2018

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 


image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By Catherine Offord | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Coriell Institute CEO Dies

Coriell Institute CEO Dies

By Kerry Grens | January 4, 2018

Michael Christman oversaw the organization’s well-known biobank and pioneered a personalized medicine initiative.


image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By Jef Akst | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.


The genome of an infant who lived in Alaska thousands of years ago represents a previously unknown group of humans called Ancient Beringians, who share a common lineage with other Native Americans. 


image: Child Receives Transgenic Skin

Child Receives Transgenic Skin

By Ruth Williams | January 1, 2018

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and resolved a dermatology debate to boot.


image: Contributors


By Jef Akst and Katarina Zimmer | January 1, 2018

Meet some of the people featured in the January 2018 issue of The Scientist.


image: David Julius Probes the Molecular Mechanics of Pain

David Julius Probes the Molecular Mechanics of Pain

By Anna Azvolinsky | January 1, 2018

For nearly 30 years, the UC San Francisco researcher has delved into unexplored corners of the nervous system.


image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.


image: Swearing Off Pain

Swearing Off Pain

By The Scientist Staff | January 1, 2018

Author Emma Byrne runs down the benefits of cursing, among them an enhanced ability to withstand pain.


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