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tag ipscs genetics genomics

RNA-Seq Reveals Previously Hidden, Genetic Disorderā€“Causing Mutations
Anna Azvolinsky | Apr 19, 2017 | 3 min read
Adding RNA sequencing analysis to genomic sequencing helps scientists uncover mutations likely responsible for genetic disorders they might otherwise miss.
CRISPR Corrects Duchenne-Causing Mutations
Anna Azvolinsky | Apr 12, 2017 | 3 min read
Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.
Pluripotent Until Needed
Beth Marie Mole | Apr 1, 2013 | 7 min read
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
Viruses Affect Cell Reprogramming
Sabrina Richards | Oct 24, 2012 | 3 min read
Viral vectors used to carry transcription factors that de-differentiate cells into a stem-cell-like state are themselves a key factor in efficient reprogramming.
Into the Limelight
Kate Yandell | Oct 1, 2015 | 8 min read
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.
Top 10 Innovations 2012
The Scientist | Dec 1, 2012 | 10+ min read
The Scientist’s 5th installment of its annual competition attracted submissions from across the life science spectrum. Here are the best and brightest products of the year.
Top Ten Innovations 2010
Megan Scudellari | Dec 1, 2010 | 10+ min read
By The Scientist Staff Top Ten Innovations 2010 Innovative products that have the life science community buzzing. As the global economy continues to pull out of its recent precipitous nosedive, one mantra rings true from Beijing to Boston—innovation can save us. If developing interesting new technologies and products really is the lifeblood of economic health, then the life sciences industry is innovation’s beating heart. The Scientist rec
2009 Top 10 Innovations
The Scientist | Dec 1, 2009 | 10+ min read
#featureArticleHeadWrapper img { border:none; float:none; margin:5px 0; }#featureArticleContent p.comment { font-weight: bold; color: #333333; font-size: 11px; line-height: 15px; }span.judge_1 { color: #E93593; } span.judge_2 { color: #20BCED; } span.judge_3 { color: #C1CD2F; } span.judge_4 { color: #F69723; } The Scientist Top 10 Innovations: 2009 The ten most exciting tools to hit the life sciences this year. It’s b
A Living Legacy
Megan Scudellari | Jan 13, 2010 | 10 min read
A Living Legacy At the birthplace of stem cell research, the next generation of scientists continues to advance the field. By Megan Scudellari In Toronto’s downtown Discovery District, world-class stem cell researchers populate the buildings like athletes at the Olympics. On University Avenue, Andras Nagy, a renowned innovator in induced pluripotent stem (iPS) cells, works at the Samuel Lunenfeld Research Institute, housed within the towering Mount Sin

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