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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Infographic: Combo Method of Stem Cell Generation

Infographic: Combo Method of Stem Cell Generation

By | December 1, 2017

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

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image: Suicide Switch for Transplanted Stem Cells

Suicide Switch for Transplanted Stem Cells

By | March 2, 2017

Researchers use an inducible gene to limit tumor growth from human iPSCs transplanted into mice.

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image: Week in Review: October 17–21

Week in Review: October 17–21

By | October 21, 2016

Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds

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image: Stem Cells Made Waves in Biology and Medicine

Stem Cells Made Waves in Biology and Medicine

By | October 1, 2016

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

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image: Thirty Years of Progress

Thirty Years of Progress

By | October 1, 2016

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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image: Review: <em>The End of Sex</em>

Review: The End of Sex

By | May 13, 2016

Legal expert Henry Greely envisions a world in which advances in biotechnology obviate the need for sexual reproduction as we know it.

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image: Skin Cells Turned Into Immature Sperm

Skin Cells Turned Into Immature Sperm

By | April 29, 2016

The reprogrammed germ-like cells were unable to fertilize eggs, however. 

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image: Monitoring Mitochondrial Mutations

Monitoring Mitochondrial Mutations

By | April 18, 2016

Induced pluripotent stem cells—particularly those generated from older patients—should be screened for defects in mitochondrial DNA, a study shows.

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