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tag insulin genetics genomics developmental biology

Developmental Genetics
Neeraja Sankaran | Sep 3, 1995 | 2 min read
E. Li, C. Beard, R. Jaenisch, "Role for DNA methylation in genomic imprinting," Nature, 366:362-5, 1993. (Cited in more than 70 publications through August 1995) Comments by Rudolf Jaenisch, Whitehead Institute for Biomedical Research, Cambridge, Mass. "The fact that DNA methylation--a modification in which methyl groups are added to cytosine residues--was involved in gene expression had been suggested for a long time," says Rudolf Jaenisch, a professor of biology at the Whitehead Institute f
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
Illustration showing two hands join, father or mother with child
Does Human Epigenetic Inheritance Deserve a Closer Look?
Catherine Offord | Apr 4, 2022 | 10+ min read
The concept of epigenetic inheritance has long been controversial. Some researchers hope that new data on cross-generational effects of environmental exposures will help settle the debate.
Recent Trials for Fragile X Syndrome Offer Hope
Randi Hagerman | Sep 1, 2019 | 10+ min read
Despite a solid understanding of the biological basis of fragile X syndrome, researchers have struggled to develop effective treatments.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Ghosts in the Genome
Oliver J. Rando | Dec 1, 2015 | 10+ min read
How one generation’s experience can affect the next
Long live the worm!
Jeff Perkel | Jun 29, 2005 | 1 min read
In tomorrow's (July 1) issue of Genes & Development, Siu Sylvia Lee, of the department of molecular biology and genetics at Cornell University in Ithaca, NY, and Gary Ruvkun, of the department of genetics at Harvard Medical School, report ?the first genome-wide functional genomic screen for longevity genes.? The two teams used a library of 16,475 RNA interference constructs (created by Julie Ahringer at the University of Cambridge, UK) to inactivate genes in the nematode, Caenorhabditis eleg
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat

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