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tag hiv vaccine ecology cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Black and gold sketch of Katalin Karikó and Drew Weissman.
Nobel Prize for mRNA Vaccines
Danielle Gerhard, PhD | Oct 2, 2023 | 5 min read
Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Systems Immunology: Understanding Responses to Vaccination and Infection
The Scientist | Mar 18, 2019 | 1 min read
The Scientist is bringing together a panel of experts to discuss their research and experiences in using systems immunology to gain new insights into immune responses to infection through single-cell data analysis, and into innate immune dysfunction in HIV infection.  
nk natural killer cell immunology immune cell adaptive innate immunity
Innate Immune Cells May Actually Remember Their Targets
Emma Yasinski | May 10, 2019 | 3 min read
Human natural killer cells, previously considered not to participate in adaptive immunity, remember viral antigens after initial exposures, according to a new study.
Vector did not kill HIV trial
Jef Akst | Jul 19, 2009 | 3 min read
New findings have disproved a leading explanation for why an experimental HIV vaccine made subjects more susceptible to the virus, reopening the door for further HIV vaccine efforts based on similar principles. Human Immunodeficiency VirusImage: NIAIDThe Merck-funded STEP study, which used an adenoviral vector to deliver an HIV vaccine candidate, was halted in 2007 after the data suggested the vaccine increased the risk of HIV infection. Researchers thought the effect might be due to an immune
Defeating the Virus
Wayne C. Koff | May 1, 2015 | 10+ min read
Recent discoveries are spurring a renaissance in HIV vaccine research and development.
Weathering Hantavirus: Ecological Monitoring Provides Predictive Model
Steve Bunk | Jul 4, 1999 | 7 min read
Photo: Steve Bunk Dave Tinnin, field research associate in the University of New Mexico's biology department, takes blood samples and measurements of rodents caught on the research station grounds. At the end of a freeway exit near Soccoro, N.M., the hairpin turn onto a gravel road is marked by a sign that warns, "Wrong Way." But it isn't the wrong way if you want to reach the University of New Mexico's (UNM) long-term ecological research (LTER) station. The sign's subterfuge is the first indi
Templates for a vaccine?
Quentin J. Sattentau and Andrew J. McMichael | Oct 1, 2010 | 4 min read
By Quentin J. Sattentau and Andrew J. McMichael Templates for a vaccine? New tools for HIV-1 antibody-based vaccine design Env is shown as a transparent mesh consisting of three gp120 molecules (red) noncovalently linked to three gp41 molecules (not modeled) on the surface of an HIV-1 virion. An area marking the CD4 binding surface is labeled yellow. Bill Schief, Dept of Biochemistry / University of Washington, Seattle The human immunodef

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