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tag broadly cross neutralizing antibodies evolution

A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Targeted Comparative Sequencing Illuminates Vertebrate Evolution
Ricki Lewis | Dec 8, 2002 | 6 min read
Image: Courtesy of Elliott Marguiles  PIPS ON PARADE: Researchers used a MultiPipMaker to show the alignments, expressed as percent identity plots, between a human reference sequence and several other species. This is a 20 kb region surrounding exon 2 of the MET gene. Gap-free alignable segments are represented as horizontal lines along the human reference sequence; the line's height represents the identity of that alignment. Aristotle envisioned humanity as the pinnacle of a "Great Chai
Week in Review: June 15–19
Tracy Vence | Jun 19, 2015 | 3 min read
Eye on MERS; HIV vaccine design; evolution of Ebola; CRISPR meets optogenetics
HIV Evolves Vulnerability
Sabrina Richards | Oct 21, 2012 | 3 min read
In mutating to evade immune detection, HIV becomes susceptible to detection by different antibodies, suggesting new strategies for vaccination.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Updated July 9
Track COVID-19 Vaccines Advancing Through Clinical Trials
The Scientist | Apr 7, 2020 | 10+ min read
Find the latest updates in this one-stop resource, including efficacy data and side effects of approved shots, as well as progress on new candidates entering human studies.
Assays Galore
Lanette Fee | Sep 21, 2003 | 9 min read
Courtesy of BD Biosciences Pharmingen  COLOR CODING: Multiplexed bead-based assays, like BD Biosciences' Cytometric Bead Array (shown), test for multiple analytes in a single vial. The key is in the colors: one hue indicates the bead ID, and the intensity of the second, how much protein has been captured. In today's fast-paced research environment, technologies for speedy, cost-efficient analyses reign supreme. As part of this general trend, techniques for multiplexing, that is, simultan
Combinatorial Libraries: Life's Tinker Toys
Gail Dutton | May 18, 2003 | 9 min read
Courtesy of UC Davis Medical Center  COMBI-KING: Kit Lam brings his expertise in combinatorial chemistry, an innovative technique for creating millions of new chemical compounds in just days, to the UC Davis Cancer Center. It's the new mix and match. In the computer industry, programmers refer to modularity--the ability to shuffle different sections of computer code to create new software. In the life sciences, the modules are peptides or molecular fragments that can be combined to yield

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