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tag infectious disease culture immunology

A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Psychoactive Drugs and Infectious Diseases
A. J. S. Rayl | Apr 16, 2000 | 10+ min read
For nearly a century, it's been known that drugs of abuse alter the immune system. Since the outbreak of the AIDS epidemic in the early 1980s, however, an explosion of data has given rise to a rapidly evolving area of research. Investigators around the world have shown that such psychoactive drugs as heroin, morphine, cocaine, and marijuana affect both the neurophysiologic and immunologic systems. In recent years, researchers have produced strong experimental evidence that these drugs of a
Transmission electron microscope image of Zika virus particles
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
Ruth Williams | May 12, 2021 | 4 min read
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
The Vaginal Microbiome is Finally Getting Recognized
Hannah Thomasy, PhD, Drug Discovery News | Sep 25, 2023 | 10+ min read
Vaginal dysbiosis has long been a taboo subject, but studying and optimizing the vaginal microbiome could be a game changer for women's health.
a newly hatched mosquito sits on top of water, with its discarded cocoon floating below
In Vitro Malaria Sporozoite Production May Lead to Cheaper Vaccines
Katherine Irving | Jan 20, 2023 | 4 min read
A method for culturing the infectious stage of the Plasmodium lifecycle could increase malaria vaccine production efficiency by tenfold, study authors say.
Patient-derived colon organoids from a healthy individual
Generating Mini-Guts for Drug Screening
The Scientist and MilliporeSigma | Dec 16, 2022 | 4 min read
Human gut organoids facilitate precise disease modeling and power high-throughput drug development efforts.
Understanding Hybridoma Technology for Monoclonal Antibody Production
Understanding Hybridoma Technology for Monoclonal Antibody Production
Alpana Mohta, MD | May 9, 2023 | 5 min read
By fusing antibody-producing cells with immortal myeloma cells, researchers produce reliable supplies of highly specific antibodies.
Bladder epithelial tissue, where cell junctions are shown in green and nuclei in blue. This was grown in vitro from cells taken from mice with chronic cystitis.
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice
Alejandra Manjarrez, PhD | Apr 12, 2023 | 3 min read
Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Infectious: Stay Away
Rowan Higgs | Jun 11, 2009 | 4 min read
An interactive exhibition in Ireland gives visitors a front row seat to the science behind epidemics

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