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tag gas chromatography mass spectrometry neuroscience culture

The mitochondria inside of a neuron are shown in red. The neuron’s protrusions called dendritic spines are shown in cyan.
How Mitochondria Stay Still in Neurons
Mariella Bodemeier Loayza Careaga, PhD | Mar 13, 2024 | 5 min read
An endoplasmic reticulum associated protein holds mitochondria in place in dendrites. This spatial stabilization possibly provides a local energy source for synaptic plasticity. 
Mass Spectrometry Applications for Proteomics
Jeffrey Perkel | Aug 19, 2001 | 10+ min read
Click to view the PDF file: Proteomic Mass Spectrometry Equipment Courtesy of CiphergenCiphergen's SELDI process, a MALDI variant that includes a surface-based enrichment step Early in the twentieth century, scientists puzzled over the observation that certain elements that were otherwise physically indistinguishable from each other nevertheless exhibited different radioactive decay characteristics. These elements would ultimately come to be known as isotopes, but at the time this concept was
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.
Green-themed conceptual illustration of a human profile with abstract patterns that represent smelling.
Disease Scent Signatures Disclose What the Nose Knows
Iris Kulbatski, PhD | Jun 12, 2023 | 4 min read
Researchers redefine the lost art of smelling illness using one woman’s exquisitely sensitive nose.
Artist’s rendition of a neuron silhouetted against a glowing red background.
SNO-y Protein Levels Help Explain Why More Women Develop Alzheimer’s
Dan Robitzski | Jan 6, 2023 | 4 min read
Female postmortem brains contain more S-nitrosylated C3 proteins, likely linked to menopause, which instruct immune cells to kill neuronal synapses.
Book Excerpt from Behave
Robert Sapolsky | May 31, 2017 | 5 min read
In the book’s introduction, author and neuroendocrinologist Robert Sapolsky explains his fascination with the biology of violence and other dark parts of human behavior.
What Kind of Mass Spec User are You?
Jeffrey M. Perkel | Feb 1, 2007 | 5 min read
Whether studying proteins, nucleic acids, or small molecules, there's an ideal configuration for everyone.
2019 Top 10 Innovations
The Scientist | Dec 1, 2019 | 10+ min read
From a mass photometer to improved breath biopsy probes, these new products are poised for scientific success.
A Test Bed for Budding Technologies
Aileen Constans | Jul 4, 2004 | 6 min read
DELETION BY DESIGN:Courtesy of Guci GiaeverThe deletion cassette module used to delete each yeast gene contains two 74-basepair tags upstream and downstream (UPTAG and DNTAG) of the KanMX gene, which confers resistance to the drug geneticin. UPTAG and DNTAG contain 18 basepairs of genomic sequence to flank the yeast's open reading frame, and U1 and U2, or D1 and D2 PCR primers for amplifying a unique 20-basepair TAG region-the so-called molecular barcode. A second round of PCR adds 45 base-pairs
Research Notes
Harvey Black | May 27, 2001 | 4 min read
Male rhesus monkeys with destroyed amygdala will abandon their normally slow and cautious familiarization process and immediately approach other monkeys with whom they are unfamiliar, according to David Amaral, professor of psychiatry and neuroscience at the University of California, Davis. His study on these animals is slated to appear in an upcoming issue of Behavioral Neuroscience. The study involved six lesioned monkeys, each meeting for many 20-minute sessions with a "stranger" monkey. The

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