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tag quantitative pcr ecology genetics genomics

Layered visual representation of multiomics
Integrate and Innovate with NGS and Multiomics
The Scientist and Illumina | May 4, 2023 | 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.
Innovations Expand Lab Power, Uses Of PCR Technique
Ricki Lewis | Jul 25, 1993 | 8 min read
The gene amplification technique invented by genetics researcher Kary Mullis on a moonlit drive through the northern California hills a decade ago--the polymerase chain reaction (PCR)-- continues to revolutionize the life sciences. Uses in molecular biology research and in diagnostic tests are proliferating, and PCR is even bringing a new molecular approach to such fields as paleontology and epidemiology. The following companies are among those supplying PCR-related products for the resear
PCR Primed To Spur Chain Of Applications
Holly Ahern | Jun 25, 1995 | 10+ min read
What would you do if your research interests revolved around obtaining DNA from a bacterium preserved for millions of years in the gut of a bee stuck in amber, matching up a murderer to crime- scene blood half a century old, or cloning genes from a 1,000- year-old mummy? Most scientists would first consider PCR--the polymerase chain reaction--as a technique for approaching problems such as these. With PCR, minute quantities of nucleic acids can be amplified millions of times into sufficient qua
Whole-Genome SNP Genotyping
Marilee Ogren | Jun 1, 2003 | 8 min read
Clockwise from top left: images courtesy of Affymetrix, Illumina, Sequenom and Illumina Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease susceptibility, environmental response, and drug metabolism. Researchers are understandably keen to dissect these variations, most of which take the form of single-nucleotide polymorphisms (SNPs). A SNP (pron
Prospecting for Gold in Genome Gulch
Amy Adams | Apr 14, 2002 | 9 min read
The human genome is much like the American West of the 1850s: Everyone wants a piece of the pie. Similar to gold prospectors of 150 years ago, biotech and pharmaceutical companies, and even universities, are frantically searching for the nuggets of gold that will help them find the mother lode—a gene whose function is sufficiently marketable to make all of the preliminary research worthwhile. Companies that do strike gold get to introduce new classes of drugs to the market. Others hope to
Creative Emulsification
Sabrina Richards | Nov 1, 2012 | 8 min read
Enhancing data collection from emulsion PCR reactions: three case studies
Diagnosing Cancer: A Genomics and Proteomics Approach
Tom Hollon | Sep 21, 2003 | 7 min read
In 1996, Jeff Trent and colleagues published the first paper describing DNA microarrays as tools for pinpointing gene variants underlying various tumor properties.1 Now, as president and scientific director of Translational Genomics Research Institute (TGEN), in Phoenix, Trent is using microarrays to look for gene expression patterns that can be applied to developing diagnostics. The role of microarrays, Trent says, "will be on the discovery side. Testing all 30,000 genes against a diagnosti
An Ocean of Viruses
Joshua S. Weitz and Steven W. Wilhelm | Jul 1, 2013 | 10+ min read
Viruses abound in the world’s oceans, yet researchers are only beginning to understand how they affect life and chemistry from the water’s surface to the sea floor.
Limber LIMS
Nicholette Zeliadt | Jan 1, 2013 | 7 min read
Using laboratory information management systems (LIMS) to automate and streamline laboratory tasks: three case studies
In Evolution's Garden
Megan Scudellari | Jun 1, 2013 | 9 min read
Raising one evolutionary question after another, Brandon Gaut has harvested a crop of novel findings about how plant genomes evolve.

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