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Spark Therapeutics’s Luxturna would be the first approved therapy in the U.S. that replaces or repairs a defective gene inherited from one’s parents.

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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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image: Study Raises Questions About Patient-Derived Xenografts

Study Raises Questions About Patient-Derived Xenografts

By Ashley P. Taylor | October 10, 2017

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.

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Scientists are using a powerful gene editing technique to understand how human embryos develop.

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image: Gene Drive Limitations

Gene Drive Limitations

By Jef Akst | October 9, 2017

In lab populations of genetically engineered mosquitoes, mutations arose that blocked the gene drive’s spread and restored female fertility.

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image: Effects of Neanderthal DNA on Modern Humans

Effects of Neanderthal DNA on Modern Humans

By Ruth Williams | October 5, 2017

A new study reveals how Neanderthal DNA in the genomes of present-day British people influences their traits.

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Tissue recipients were treated as “guinea pigs,” says investigation leader.

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Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.

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image: Q&A with Michael Young, Nobel Laureate

Q&A with Michael Young, Nobel Laureate

By Ashley P. Taylor | October 2, 2017

Young talks with The Scientist about studying circadian rhythms in fruit flies, the applications of his work beyond Drosophila, and winning the prize. 

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image: Q&A with Nobel Laureate Michael Rosbash

Q&A with Nobel Laureate Michael Rosbash

By Ashley Yeager | October 2, 2017

A basic curiosity about how life works led the Brandeis University molecular biologist to discover how our bodies keep time. 

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