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tag adeno associated virus developmental biology disease medicine neuroscience

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Developmental Neuroscience Blossoming In The 1990s
Neeraja Sankaran | Nov 13, 1994 | 5 min read
Society for Neuroscience 11 Dupont Circle, N.W.Suite 500 Washington, D.C. 20036 Phone: (202) 462-6688 Nancy Beang, executive director Carla Shatz, president 23,000 members International Society for Developmental Neuroscience University of Texas Medical Branch Galveston, Texas 77550-0652 Phone: (409) 772-3667 Fax: (409) 772-8028 E-mail: regino@beach.utmb.edu Arne Schousboe, president Regino Perez-Polo, secretary-general 1,000 m
Developmental Neuroscience Blossoming In The 1990s
Neeraja Sankaran | Nov 13, 1994 | 5 min read
Society for Neuroscience 11 Dupont Circle, N.W.Suite 500 Washington, D.C. 20036 Phone: (202) 462-6688 Nancy Beang, executive director Carla Shatz, president 23,000 members International Society for Developmental Neuroscience University of Texas Medical Branch Galveston, Texas 77550-0652 Phone: (409) 772-3667 Fax: (409) 772-8028 E-mail: regino@beach.utmb.edu Arne Schousboe, president Regino Perez-Polo, secretary-general 1,000 m
Amyloid plaques on axons of neurons
The Misunderstood Proteins of Neurodegeneration
Catherine Offord | Aug 1, 2022 | 10+ min read
The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the development of disease.
How Manipulating Rodent Memories Can Elucidate Neurological Function
Amber Dance | May 1, 2020 | 10+ min read
Strategies to make lab animals forget, remember, or experience false recollections probe how memory works, and may inspire treatments for neurological diseases.
Getting Drugs Past the Blood-Brain Barrier
Amanda B. Keener | Nov 1, 2017 | 10+ min read
To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018 | 4 min read
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
Gene Therapists Aim for Parkinson's Disease
Douglas Steinberg | Oct 1, 2001 | 7 min read
At first blush, gene therapy seems ill-suited to treating Parkinson's disease (PD). Scientists have linked few cases to missing or mutated genes and are generally clueless about the disease's cause. But the need for some relief from its debilitating symptoms is so great that gene therapy researchers have labored over the past decade to develop counter-strategies. These studies have had promising results. When the brains of rat and monkey PD models express certain transgenes, the animals show les
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.

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