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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Top 7 in Molecular Biology
Cristina Luiggi | Aug 16, 2011 | 3 min read
A snapshot of the most highly ranked articles in molecular biology, from Faculty of 1000
translation gene genetics ribosome enhancers knowable magazine
What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, and Knowable Magazine | May 3, 2019 | 8 min read
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Weathering Hantavirus: Ecological Monitoring Provides Predictive Model
Steve Bunk | Jul 4, 1999 | 7 min read
Photo: Steve Bunk Dave Tinnin, field research associate in the University of New Mexico's biology department, takes blood samples and measurements of rodents caught on the research station grounds. At the end of a freeway exit near Soccoro, N.M., the hairpin turn onto a gravel road is marked by a sign that warns, "Wrong Way." But it isn't the wrong way if you want to reach the University of New Mexico's (UNM) long-term ecological research (LTER) station. The sign's subterfuge is the first indi
Those We Lost in 2018
Ashley Yeager | Dec 26, 2018 | 10+ min read
The scientific community said goodbye to a number of leading researchers this year.
Playing Protein Hide and Seek
Mignon Fogarty | Apr 11, 2004 | 6 min read
LIGHTING THEIR LOCATIONS:© 2002 Cold Spring Harbor PressImmunolocalization of epitope-tagged proteins. (A-E) represent cells containing HAT-tagged proteins stained with the DNA dye, DAPI, and a monoclonal antibody against hemagluttinin, α-HA. At right the images are merged. (F-J) indicates cells carrying V5 tagged proteins. The bar equals 2 μm.Aliens sifting through the remains of a lost human civilization might puzzle over the function of a ladle. But if found in a room associate
Mitochondria from Different Brain Cells Have Different Proteins
Jef Akst | Dec 1, 2019 | 3 min read
Organelles isolated from two types of neurons and a nonneuronal astrocyte in the mouse cerebellum showed varying levels of proteins, hinting at functional differences.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
A C-fern (Ceratopteris richardii) growing in a pot
Genome Spotlight: C-fern (Ceratopteris richardii)
Christie Wilcox, PhD | Sep 22, 2022 | 5 min read
Sequences for the model organism and two of its kin reveal how these plants got their oversized genomes.

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