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tag chromosome folding domains ecology cell molecular biology

The structure of a biological cell (macro)
The Long and Winding Road to Eukaryotic Cells
Amanda Heidt | Oct 17, 2022 | 10+ min read
Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Artist’s rendition of red SARS-CoV-2 coronaviruses floating near blue strands of DNA.
COVID-19 Infections May Reshape Genetic Landscape
Holly Barker, PhD | Mar 30, 2023 | 3 min read
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 
The Archaeal Domain
Myrna Watanabe | May 29, 1994 | 7 min read
Future Uses Author: MYRNA E. WATANABE, pp.14 Date: May 30,1994 They live--thrive, even--in boiling water! They feed on sulfur or hydrogen. They could be from one of the moons of Jupiter. In fact, their existence here on Earth has led scientists to realize that planets they hitherto assumed to be lifeless might support life. These thermophilic, or heat-loving, microbes--Archaea--are attracting a small but growing cadre of researcher
The Archaeal Domain
Myrna Watanabe | May 29, 1994 | 7 min read
Future Uses Author: MYRNA E. WATANABE, pp.14 Date: May 30,1994 They live--thrive, even--in boiling water! They feed on sulfur or hydrogen. They could be from one of the moons of Jupiter. In fact, their existence here on Earth has led scientists to realize that planets they hitherto assumed to be lifeless might support life. These thermophilic, or heat-loving, microbes--Archaea--are attracting a small but growing cadre of researcher
Going Beneath the Fold
Robert Mahley and Yadong Huang | Aug 1, 2006 | 10+ min read
FEATUREProtein Misfolding Transmission Electron Micrograph of Protein Filaments in Alzheimer's DiseaseCOURTESY OF HUNTINGTON POTTERHow an apolipoprotein E isoform wreaks havoc in the brain, and what we might be able to do about itBY ROBERT MAHLEY AND YADONG HUANGFor much of the 20th century, scientists have looked at brain cells from patients with Alzheimer's disease (AD), Huntington's disease, and other neurodeg
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Archaea Family Tree Blossoms, Thanks to Genomics
Amber Dance | Jun 1, 2018 | 10+ min read
Identification of new archaea species elucidates the domain’s unique  biology and sheds light on its relationship to eukaryotes.

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