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tag tumor heterogeneity evolution disease medicine

A compilation of several images, including a dog, a blind mole rat, and cell micrographs
Our Favorite Cancer Stories of 2021
Amanda Heidt | Dec 9, 2021 | 4 min read
This year revealed just how much scientists have learned about the disease, from how animals become naturally cancer-resistant to how tumor cells harness extracellular DNA to develop rapid drug resistance.
Cancer’s Escape Routes
Tia Ghose | Nov 29, 2011 | 5 min read
Scientists are beginning to discover myriad strategies tumors use to avoid attacks by anti-cancer drugs.
multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Control ALT, Delete Cancer
Haroldo Silva, David Halvorsen, and Jeremy D. Henson | Apr 1, 2015 | 5 min read
Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway
artificial intelligence feature the scientist
AI Uses Images and Omics to Decode Cancer
Amber Dance | May 1, 2019 | 10 min read
Machine learning can analyze photographs of cancer, tumor pathology slides, and genomes. Now, scientists are poised to integrate that information into cancer uber-models.
Cancer Evolutionist: A Profile of Charles Swanton
Anna Azvolinsky | Apr 1, 2018 | 9 min read
Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.
Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
Samuel F. Bakhoum | Mar 1, 2022 | 10+ min read
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
An Epi Phenomenon
Karen Hopkin | Dec 1, 2012 | 9 min read
While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.
Antibody Alternatives
Paul Ko Ferrigno and Jane McLeod | Feb 1, 2016 | 10+ min read
Nucleic acid aptamers and protein scaffolds could change the way researchers study biological processes and treat disease.

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