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tag high content screening immunology disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Patient-derived colon organoids from a healthy individual
Generating Mini-Guts for Drug Screening
The Scientist and MilliporeSigma | Dec 16, 2022 | 4 min read
Human gut organoids facilitate precise disease modeling and power high-throughput drug development efforts.
Illustration of woman looking at floating cells through a telescope
Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity
Jane Buckner, MD and Carla Greenbaum, MD | Mar 1, 2023 | 4 min read
A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
An illustration of a pregnant women wearing a mask, surrounded by microbes
How COVID-19 Affects Pregnancy
Amanda Heidt | Aug 16, 2022 | 10 min read
Evidence thus far shows that pregnant people infected with SARS-CoV-2 are at higher risk for severe disease and death, as well as complications in their pregnancies.
Microscopic Bowls Uncover the Secrets of Protein Secretions
Rebecca Roberts, PhD | Jan 30, 2024 | 4 min read
Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell. 
A person lying on a bed checks the reading on a digital thermometer. A table with a bowl of oranges and various medications is in the background.
How Mild Is Omicron Really?
Dan Robitzski | Jan 14, 2022 | 9 min read
Early reports that Omicron causes less-severe disease than Delta seem to be borne out, but it’s not yet clear to what extent that’s due to the variant itself versus the populations it’s infecting.
A surgical mask next to an open pill bottle that’s toppled over, spilling out red capsules meant to represent vitamin D supplements.
Vitamin D Likely Doesn’t Prevent COVID-19, Studies Find
Dan Robitzski | Sep 9, 2022 | 2 min read
The results from two large clinical trials don't support the idea that supplements of the vitamin bolster immune defenses against SARS-CoV-2.

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