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tag hygiene hypothesis developmental biology evolution cell molecular biology

One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
A Summing Up, and a Look Ahead, in Biology
Patrick Wigge | Jun 11, 2000 | 5 min read
Illustration: A. Canamucio Biology today, though uncovering more and more knowledge at an amazingly rapid rate, is more specialized, fragmented, and incomprehensible to the layperson than ever. Part of this is inevitable, due to the rapid expansion of knowledge brought about by the great advances of molecular techniques. However, disciplinary boundaries are also part of the problem. Could we not try to overcome such obstacles and integrate some of the many strands of knowledge, to see what we mi
New beta cells without stem cells?
Kerry Grens | May 28, 2007 | 3 min read
Two studies find adult pancreatic cells maintain islet population, contradicting a hypothesis that regeneration relies on stem cells
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
A semi-translucent hydra, complete with a body column, head, and multiple tentacles, is pictured in front of a gray background.
How Hydras Regenerate Decapitated Heads
Dan Robitzski | Dec 14, 2021 | 5 min read
Hydra vulgaris constantly replenish the cells in their heads and grow new ones to reproduce asexually. But gene expression analyses reveal that regenerating a head after an injury is a very different process.
The Ever-Transcendent Cell
John S. Torday | Nov 1, 2014 | 6 min read
Deriving physiologic first principles
Plague Genome: The Evolution Of a Pathogen
Ricki Lewis | Oct 28, 2001 | 7 min read
Plague has earned a place in history books as the Black Death of medieval Europe, and in novels, from Albert Camus' classic The Plague, to the more recent Year of Wonders.1,2 A different medium for telling the tale of the plague bacterium Yersinia pestis is its genome, recently sequenced by researchers at the Sanger Centre, the London School of Hygiene and Tropical Medicine, the Royal London School of Medicine and Dentistry, and the Imperial College of Science, Technology and Medicine.3 In addi
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.

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