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image: Mitochondrial DNA Plays a Role in Metastasis

Mitochondrial DNA Plays a Role in Metastasis

By Kerry Grens | April 18, 2018

Experiments in mice show that mitochondria, both within the tumor and beyond, can make the difference between promoting or inhibiting cancer spread.

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Treating mice with anti-inflammatory drugs following surgery reduced the size of tumors.

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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image: Of Mice and Metastasis

Of Mice and Metastasis

By Amanda B. Keener | April 1, 2018

Tools for studying how cancer spreads

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Errors in segregation during cell division can lead to inflammation in daughter cells.

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image: Macrophages Play a Double Role in Cancer

Macrophages Play a Double Role in Cancer

By Amanda B. Keener | April 1, 2018

Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.

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image: Is the Interstitium Really a New Organ?

Is the Interstitium Really a New Organ?

By Abby Olena | March 28, 2018

A study confirms that the spaces between cells are fluid-filled, rather than tightly packed with connective tissue, but pathologists say the findings’ implications remain to be seen.

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Testing treatments on mini tumors may save time in identifying which therapies work best, a new study shows.   

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The treatment also curbed the growth of nearby metastases that did not receive the drug.

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By Shawna Williams | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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