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tag generics culture

Recent Trials for Fragile X Syndrome Offer Hope
Randi Hagerman | Sep 1, 2019 | 10+ min read
Despite a solid understanding of the biological basis of fragile X syndrome, researchers have struggled to develop effective treatments.
The Little Cell That Could
Megan Scudellari | Jul 1, 2012 | 7 min read
Critics point out that cell therapy has yet to top existing treatments. Biotech companies are setting out to change that—and prove that the technology can revolutionize medicine.
Cookbook For Eukaryotic Protein Expression: Yeast, Insect, and Plant Expression Systems
Christopher Smith | Nov 8, 1998 | 10+ min read
Date: November 9, 1998Baculovirus Expression Vectors In the recent past, efforts to elucidate the relationship between protein structure and biological function have intensified. Of particular interest is an understanding of the elements of sequence and structure that mediate specific functions. Often the protein of interest is in low abundance in its natural source and can be difficult to purify and/or unstable--subject to proteolytic cleavage or unfolding/non specific refolding during exhaust
Intelligent Redesign
Ishani Ganguli | Aug 1, 2006 | 7 min read
FEATURELab Design   Main image: © Getty ImagesSmaller images: Justin MacNochie Photography/SmithgroupWith billions being spent on new labs and renovations, do shinier labs really make for better science? BY ISHANI GANGULIARTICLE EXTRASRelated Articles:Lab Rehab Redesign and the Bottom Line It's Easy Going GreenAnatomy of an energy-sustainable lab renovationWeb Extra:Lab Rehab: Laying out other options
A Paradigm Shift in Stem Cell Research?
Ricki Lewis | Mar 5, 2000 | 9 min read
Photo: E.D. Laywell, UT MemphisMultipotent clones of cells derived from the adult human brain With the promises and challenges of stem cell research in the headlines, visions of artificial livers dance in the public's eye. Bioethicists, politicians, and citizens alike continue to debate whether public funds should be used to obtain cells from human embryos and fetuses. On the scientific front, however, the implications of stem cell research are even more profound than offering replacement parts.
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Variations on a Gene
Amy Francis | Jul 23, 2000 | 10+ min read
Photodisc Although President Bill Clinton surely had something in mind during his 2000 State of the Union address when he asked the nation to "celebrate our diversity," insights into human diversity at the molecular level are promising to speed drug discovery and revolutionize medicine to mark- edly improve human health. Individuals differ at one in 1,000 base pairs, which adds up to a whopping number of human genetic variations when applied to the roughly three billion base pairs of the human g
Flow Cytometry
Josh Roberts | May 4, 2003 | 8 min read
Courtesy of DakoCytomation Conventional wisdom holds that flow cytometers are expensive, massive, high-maintenance instruments that require trained operators. They are plumbed into centralized facilities of large institutions, where investigators can pay to have their cells sorted, or perform the analyses themselves (provided they have the requisite skills) under the watchful eye of the center's personnel. But as so often happens, the conventional wisdom is wrong. Nowadays, flow cytometers ar
Ultimate Abs
Deborah Wilkinson | Apr 16, 2000 | 10+ min read
Antibody Purification Reagents The immune response is often exploited to produce those remarkably useful affinity reagents known as antibodies. Today's biological and biomedical laboratories employ an array of different immunochemical techniques. For example, a specific antibody can be harnessed to screen for the presence of its respective antigen, quantify the amount of antigen in a given sample, determine the antigen's subcellular location, isolate the antigen from complex mixtures, and sear

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