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image: Immunotherapy More Effective in Men: Study

Immunotherapy More Effective in Men: Study

By Kerry Grens | May 18, 2018

Women with metastatic cancer who were treated with a checkpoint inhibitor had a smaller benefit than did men.

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image: Mitochondrial DNA Plays a Role in Metastasis

Mitochondrial DNA Plays a Role in Metastasis

By Kerry Grens | April 18, 2018

Experiments in mice show that mitochondria, both within the tumor and beyond, can make the difference between promoting or inhibiting cancer spread.

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Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  

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image: Cancer Evolutionist: A Profile of Charles Swanton

Cancer Evolutionist: A Profile of Charles Swanton

By Anna Azvolinsky | April 1, 2018

Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.

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image: Transgenic Mouse Illuminates Melanoma Metastasis

Transgenic Mouse Illuminates Melanoma Metastasis

By Abby Olena | June 28, 2017

Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 

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image: Cancer Studies Seem Replicable

Cancer Studies Seem Replicable

By Kerry Grens | June 27, 2017

In the latest findings from the Reproducibility Project: Cancer Biology, independent researchers achieve results that mirror those of two earlier papers.

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image: Immune Cells Deliver Cancer Drugs to the Brain

Immune Cells Deliver Cancer Drugs to the Brain

By Diana Kwon | June 19, 2017

Neutrophils loaded with the chemotherapy drug paclitaxel traverse the blood-brain barrier and kill residual cancer cells after tumor-resection surgery in mice.

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image: Trump Picks National Cancer Institute Director

Trump Picks National Cancer Institute Director

By Kerry Grens | June 12, 2017

Ned Sharpless currently leads the cancer center at the University of North Carolina, Chapel Hill.

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image: Rare T Cells Fight Cancer

Rare T Cells Fight Cancer

By Jef Akst | May 1, 2017

A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.

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In the middle of the 20th century, the National Cancer Institute began testing plant extracts for chemotherapeutic potential—helping to discover some drugs still in use today.

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