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tag phage display evolution culture

A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Evolution outside the lab
Hannah Waters | Mar 30, 2011 | 2 min read
Bacteria and their parasitic phages evolve just as quickly in a natural soil community as they do in a test tube, but other selective pressures can influence the changes
Bacteriophages to the Rescue
Emily Monosson | Jul 16, 2017 | 3 min read
Phage therapy is but one example of using biological entities to reduce our reliance on antibiotics and other failing chemical solutions.
The Ties That Bind: Peptide Display Technology
Debra Swanson | Mar 14, 1999 | 10+ min read
Date: March 15, 1999 Phage Display Systems and Vectors Structure of the T7 phage particle. The negative-stained pattern from polyheads showing capsid hexamer and pentamer units has been fitted onto the surface of the icosahedral particle. A single monomer of the capsid protein is shaded in red. Figure provided by Novagen. Back in the early '50s, at a time when Elvis Presley was beginning his undisputed reign as the king of rock 'n' roll, bacteriophage were rearing their ugly heads (so to spe
Protein or Perish
Ruth Williams | Aug 31, 2016 | 1 min read
A bacteriophage must evolve certain variants of a protein or die.
Targeting Antibiotic-Resistant Bacteria with CRISPR and Phages
Anna Azvolinsky | May 18, 2015 | 3 min read
Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 
Going Viral
Breeann Kirby and Jeremy J. Barr | Sep 1, 2013 | 10+ min read
From therapeutics to gene transfer, bacteriophages offer a sustainable and powerful method of controlling microbes.
Targeted Comparative Sequencing Illuminates Vertebrate Evolution
Ricki Lewis | Dec 8, 2002 | 6 min read
Image: Courtesy of Elliott Marguiles  PIPS ON PARADE: Researchers used a MultiPipMaker to show the alignments, expressed as percent identity plots, between a human reference sequence and several other species. This is a 20 kb region surrounding exon 2 of the MET gene. Gap-free alignable segments are represented as horizontal lines along the human reference sequence; the line's height represents the identity of that alignment. Aristotle envisioned humanity as the pinnacle of a "Great Chai
Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018 | 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  

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