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image: Opinion: We Have Been Naive About Naive T Cells

Opinion: We Have Been Naive About Naive T Cells

By Theo van den Broek, José A.M. Borghans, and Femke van Wijk | April 6, 2018

Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.

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image: Ruth Nussenzweig, Malaria Researcher, Dies

Ruth Nussenzweig, Malaria Researcher, Dies

By Jim Daley | April 6, 2018

The microbiologist’s research led to the development of the first human malaria vaccine.

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image: A Neuroscientist’s Journey Through Madness

A Neuroscientist’s Journey Through Madness

By Barbara Lipska with Elaine McArdle | April 1, 2018

After I was diagnosed with brain cancer and started to lose my mental health, the importance of my job came into clear focus.

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Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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Errors in segregation during cell division can lead to inflammation in daughter cells.

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The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.

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A study finds that the vaccine’s effects wear off as a person ages, suggesting a need for booster shots.

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In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.

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image: Eat Yourself to Live: Autophagy’s Role in Health and Disease

Eat Yourself to Live: Autophagy’s Role in Health and Disease

By Vikramjit Lahiri and Daniel J. Klionsky | March 1, 2018

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

4 Comments

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