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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

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image: Image of the Day: Actin Burst

Image of the Day: Actin Burst

By The Scientist Staff | December 6, 2017

Researchers are looking at actin polymerization and calcium uptake in human cells to study mitochondrial division.

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image: Captivated by Chromosomes

Captivated by Chromosomes

By Anna Azvolinsky | December 1, 2017

Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.

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image: In Situ Hybridization Explained

In Situ Hybridization Explained

By The Scientist Staff | December 1, 2017

Profilee Joseph Gall of the Carnegie Institute describes the process, which he developed in the 1960s.

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The Lawrence Berkeley National Laboratory researcher’s work will help predict how the Arctic is responding to climate change—and the global effects of those changes.

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image: Passing the Torch

Passing the Torch

By Mary Beth Aberlin | December 1, 2017

Looking back, looking forward

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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By Ruth Williams | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Infographic: Combo Method of Stem Cell Generation

Infographic: Combo Method of Stem Cell Generation

By Ruth Williams | December 1, 2017

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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