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tag double helix disease medicine developmental biology

Tara Kieffer: From helix to hepatitis
Katherine Bagley | Jan 1, 2010 | 3 min read
By Katherine Bagley Tara Kieffer: From helix to hepatitis © 2009 Leah Fasten Tara Kieffer fell in love with science during a visit to her father’s biology lab at Montgomery College in Maryland. Inspired by a model of DNA’s double helix, the 5- or 6-year-old Kieffer drew a replica of the structure that has hung on her walls ever since. “DNA was beautiful and it helped spark my interest in biology,” she says. Whil
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
Aging and Cancer
Aging and Cancer
Rebecca Roberts, PhD | Nov 14, 2023 | 6 min read
The relationship between aging and cancer is complex, with several shared underlying mechanisms. 
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021 | 4 min read
A key mutation turns healing cells into cancer promoters.
Metaphors and Dreams
Tim Radford | Jan 12, 2003 | 7 min read
The DNA revolution may be just too big to take in: beyond words, even 50 years on. Think of four chemical bases coupled exclusively to each other, adenine with thymine, guanine with cytosine, in a double helix. Then think of this double helix having the power to unwind and duplicate, to make new helixes. So far, so simple. The structure spells out a gene that makes a protein, and makes more DNA. But like the double helix itself, the challenges divide into questions of scale and complexity. In
Decoding DNA: New Twists and Turns
Kerry Grens | Jun 1, 2013 | 10+ min read
Highlights from a series of three webinars on the future of genome research, held by The Scientist to celebrate 60 years of the DNA double helix
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | Aug 31, 2022 | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018 | 10+ min read
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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