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tag sleep wake cycle cell molecular biology

Researchers Uncover Sleep/Wake Gene
Eugene Russo | Aug 16, 1998 | 4 min read
Recent research has shed new light on the sleep/wake cycle. In two papers featured on the cover of the July 10 issue of Cell (J.L. Price et al., Cell, 94:83-95, 1998; B. Kloss et al., Cell, 94:97-107, 1998), scientists from Rockefeller University reported the discovery of a gene in Drosophila, dubbed double-time (dbt). The dbt gene is believed to regulate the molecular cycles underlying circadian rhythms--patterns of activity that, in humans, regulate body temperature, mental alertness, pain
You Are When You Eat
Iris Kulbatski, PhD | Nov 20, 2023 | 3 min read
Intermittent fasting regulates biological time and improves disrupted sleep in an Alzheimer’s disease model.
A Good Night’s Sleep
Edyta Zielinska | Sep 1, 2012 | 2 min read
Sleep-wake cycles affect how well our bodies fight disease.
Astrocytes, Not Just Neurons, Play a Role in Sleep
Abby Olena, PhD | Sep 24, 2020 | 4 min read
In mice, the brain’s main glial cell type exhibits distinctive patterns of activity across the sleep-wake cycle and influences the response to sleep deprivation.
Time, Flies
Anna Azvolinsky | Nov 1, 2016 | 9 min read
By studying the sleep-wake cycle of fruit flies, Amita Sehgal is revealing how the body’s circadian and sleep rhythms are regulated.
Lasker Award winner Piet Borst sits at his desk.
A Journey With Metabolism, Parasites, and Cancer
Laura Tran, PhD | Sep 21, 2023 | 7 min read
Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.
Out-of-Sync Light and Heat Levels Disrupt the Body’s Clock
Ben Andrew Henry | Nov 8, 2016 | 2 min read
Six-hour time lags between daily cycles of light and heat lead the molecular pathways that help fruit flies keep track of time to go haywire.
Genetic And Molecular Mysteries Of Sleep Are Keeping Researchers Alert
Alison Mack | Oct 27, 1996 | 9 min read
SIDEBAR : Sleep Research Resources Some consider sleep an unavoidable nuisance; others, a sweet indulgence. For the most part, though, we take our slumber for granted, rarely considering why we spend a hefty chunk of our lives unconscious. But for sleep researchers, that question represents a supreme mystery. Exactly what purpose sleep serves, as well as how the body regulates sleeping and waking, remain largely unknown. Behavioral scientists and physiologists have pursued these questions for
Sleep’s Kernel
Sandip Roy and James M. Krueger | Mar 1, 2016 | 10 min read
Surprisingly small sections of brain, and even neuronal and glial networks in a dish, display many electrical indicators of sleep.

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