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tag nanoscale imaging culture neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Brain cell in purple on a black background. Arc mRNAs are labeled green and are mainly localized in the cell nucleus and in the dendrites.
Short-lived Molecules Support Long-term Memory 
Alejandra Manjarrez, PhD | Jun 6, 2023 | 3 min read
A gene essential for information storage in the brain engages an autoregulatory feedback loop to consolidate memory.
This image depicts the fruit fly nerve cord connectome. It highlights 930 neurons, a subset of the full set of reconstructed neurons.
The Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 6 min read
A series of technological advancements for automation and parallel imaging made volume electron microscopy more user friendly while increasing throughput.
New and Old Techniques in Modern Neuroscience
Alison F. Takemura | Oct 1, 2016 | 6 min read
Imaging and manipulating the brain has come a long way from electrodes and the patch clamp, though such traditional tools remain essential.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Book Excerpt from When Brains Dream
Robert Stickgold and Antonio Zadra | Dec 1, 2020 | 8 min read
Ferreting out the biological function of dreaming is a frontier in neuroscience.
Scientists Stretch Neurons to Image Fine Structures
Kerry Grens | Apr 18, 2017 | 1 min read
A double-expansion technique embeds brain tissue in the absorbent material of diapers to stretch out cells for easier visualization.
Opinion: The Biological Function of Dreams
Robert Stickgold and Antonio Zadra | Dec 1, 2020 | 3 min read
The scenarios that run through our sleeping brains may help us explore possible solutions to concerns from our waking lives.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Building Nanoscale Structures with DNA
Arun Richard Chandrasekaran | Jul 16, 2017 | 10+ min read
The versatility of geometric shapes made from the nucleic acid are proving useful in a wide variety of fields from molecular computation to biology to medicine.

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