Vicki Colvin | Aug 29, 2004 | 6 min read
FIGURE 1:Courtesy of Vicki ColvinThe cytotoxicity of three fullerene derivatives in cell culture (human dermal fibroblasts, 48-hour exposures). As the derivatization of the fullerene surface changes from a sparingly soluble version (black) to a fully hydroxylated material (blue), the dose that kills half the cells changes over many orders of magnitude. This result highlights the importance of surface coatings and derivatizations to biological activity.When materials and devices are fabricated wi