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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By Amanda B. Keener | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Genetic Risk Factors for Breast Cancer Identified

Genetic Risk Factors for Breast Cancer Identified

By Ashley P. Taylor | October 23, 2017

Researchers identify 72 novel genetic variants associated with breast cancer risk.

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image: Sequencing Genomes in the ICU Improves Outcomes

Sequencing Genomes in the ICU Improves Outcomes

By Bob Grant | October 19, 2017

A handful of infants in a neonatal intensive care unit who were diagnosed with rare diseases using whole-genome sequencing had shorter hospital stays and better health outcomes, researchers find.

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image: Compound Found in Red Wine Boosts Immune Cell Function

Compound Found in Red Wine Boosts Immune Cell Function

By Catherine Offord | October 17, 2017

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 

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A needle-free alternative to the finger-prick test would be a godsend for many sufferers of diabetes, but the industry has yet to clear the technological hurdles.

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Spark Therapeutics’s Luxturna would be the first approved therapy in the U.S. that replaces or repairs a defective gene inherited from one’s parents.

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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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Tissue recipients were treated as “guinea pigs,” says investigation leader.

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