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tag bone fracture cell molecular biology

A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
The Bare Bones of Animal Imaging
Linda Sage | Feb 27, 2005 | 2 min read
Eastman Kodak of Rochester, NY, has developed a module for its Image Station 2000MM Multimodal Imaging System that precisely coregisters X-ray images of lab animals with fluorescent, luminescent, or radioisotopic images generated using molecular markers.
Loss in Space
Harvey Black | Apr 28, 2002 | 5 min read
When transatlantic steamers traversed the oceans, one line touted itself with ads saying: "Getting there is half the fun." Not so with space travel: Here, an unhealthy situation exists because the travelers' bones lose mass and weaken. Severe bone loss leads to fractures. A recent Institute of Medicine (IOM) report labeled bone loss as one of the most serious problems facing those who would make long-duration space voyages, such as traveling to Mars.1 Until now, space scientists had information
Human Mesenchymal Stem Cells Differentiate in the Lab
Ricki Lewis | Apr 11, 1999 | 5 min read
While prominent scientists plead with legislators to reconsider their conservative stance on funding human embryonic stem (ES) cell research, a six-year-old company in Baltimore is quietly making the matter moot. In a just-released tour-de-force research report, it is no longer quite so quiet.1 Researchers at Osiris Therapeutics and the Johns Hopkins University School of Medicine coaxed human mesenchymal stem cells (hMSCs) from adults' bone marrow to develop into cartilage, fat, and bone cells
Cancer-Enhancing Stress
Hayley Dunning | Jul 17, 2012 | 2 min read
Depression in post-op breast cancer patients can cause tumors to establish in bone.
translation gene genetics ribosome enhancers knowable magazine
What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, and Knowable Magazine | May 3, 2019 | 8 min read
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
New beta cells without stem cells?
Kerry Grens | May 28, 2007 | 3 min read
Two studies find adult pancreatic cells maintain islet population, contradicting a hypothesis that regeneration relies on stem cells
The Delicate Balancing Act
Laura Defrancesco | Mar 3, 2002 | 4 min read
For this article, Laura DeFrancesco interviewed Lorenz Hofbauer, head of the Molecular Bone Biology Laboratory at Philipps University, Marburg, Germany; Colin Dunstan, senior research scientist, Amgen Inc., in Thousand Oaks, Calif., and Sundeep Khosla, professor of medicine, Mayo Medical School. Data from the Web of Science show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. L.C. Hofbauer, S. Khosla, C.R. Dunstan, et al., "The roles of oste
How to Track Cell Lineages As They Develop
Kelly Rae Chi | Dec 1, 2016 | 7 min read
Sequencing and gene-editing advances make tracing a cells journey throughout development easier than ever.
Innovations Expand Lab Power, Uses Of PCR Technique
Ricki Lewis | Jul 25, 1993 | 8 min read
The gene amplification technique invented by genetics researcher Kary Mullis on a moonlit drive through the northern California hills a decade ago--the polymerase chain reaction (PCR)-- continues to revolutionize the life sciences. Uses in molecular biology research and in diagnostic tests are proliferating, and PCR is even bringing a new molecular approach to such fields as paleontology and epidemiology. The following companies are among those supplying PCR-related products for the resear

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