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tag salivary gland culture genetics genomics

Tissue Microarrays: Advancing Clinical Genomics
Jeffrey Perkel | Oct 27, 2002 | 8 min read
Image: Courtesy of Biocat SCORES OF CORES: Each tissue core on this microarray provides another datapoint that helps researchers better define the molecular characteristics of interesting genes. In 1997, Juha Kononen, a postdoctoral fellow at the National Human Genome Research Institute, was pondering the significance of the recently developed DNA microarray. He was studying genetically altered genes in cancerous cells using fluorescence in situ hybridization and immunostaining of indivi
Stopping the Cycle
Melissa Lee Philips | Aug 1, 2006 | 7 min read
Stefan Kappe's insights into parasite development have already led to a live malaria vaccine for mice.
Fearless about Folding
Anna Azvolinsky | Jan 1, 2016 | 9 min read
Susan Lindquist has never shied away from letting her curiosity guide her research career.
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
Shock and Age
RICHARD MORIMOTO | Jun 1, 2010 | 10+ min read
BY RICHARD MORIMOTO Shock and Age The accumulation of misfolded protein marks the accrual of years as the body ages. Could heat shock proteins be used to reduce the effects of aging and diminish the risk of disease by untangling improperly folded proteins? © Thom Graves What does a molecular thermometer look like? This seemed to be a simple question, not much different from the many science fair projects I had done in grade school and high school
Evolution, Resisted
Elie Dolgin | Oct 1, 2009 | 10+ min read
Scientists are trying to design the last malaria control agent the world will ever need.
West Nile Virus--Part 2?
Ricki Lewis | Apr 16, 2000 | 8 min read
Graphic: Cathleen Heard When the days grew short enough by last November to finally send mosquitoes away from the backyards and parks of New York City, residents and public health officials alike breathed a collective sigh of relief. Mosquitoes has brought West Nile virus encephalitis, sickening 62 and killing seven. Lingering worst-case scenarios envisioned virus-ridden mosquitoes overwintering in the subways, emerging come springtime to spread disease again. As those outside the Apple joked ab

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