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image: First CAR T-Cell Therapy Approved in U.S.

First CAR T-Cell Therapy Approved in U.S.

By Shawna Williams | August 30, 2017

The genetically modified blood cells will be used for patients with a type of acute lymphoblastic leukemia, when other treatments fail.

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image: FDA Votes Yes on CAR T-Cell Therapy

FDA Votes Yes on CAR T-Cell Therapy

By Aggie Mika | July 13, 2017

A Food and Drug Administration advisory panel unanimously calls for agency approval of the cell therapy for the treatment of resistant leukemia. 


image: Gene Editing Treats Leukemia

Gene Editing Treats Leukemia

By Karen Zusi | November 6, 2015

One-year-old Layla Richards has remained cancer-free months after receiving an experimental gene editing therapy.


image: Tumor-Targeting T Cells Engineered

Tumor-Targeting T Cells Engineered

By Chris Palmer | August 11, 2013

Scientists genetically modify T cells derived from pluripotent stem cells to attack lymphatic tumors.


image: Immune System Versus Cancer

Immune System Versus Cancer

By Dan Cossins | April 10, 2013

Engineering the immune system to overcome tumor evasion strategies was a hot topic at this week’s AACR meeting, with researchers discussing several new approaches.


image: Leukemia Linked to Changes in Womb

Leukemia Linked to Changes in Womb

By Edyta Zielinska | April 10, 2013

Genetic changes that may initiate childhood leukemia could originate while the baby is still in utero.


image: Contributors


By Kate Yandell | April 1, 2013

Meet some of the people featured in the April 2013 issue of The Scientist.


image: Up, Up, and Array

Up, Up, and Array

By Megan Scudellari | April 1, 2013

By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.

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