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“Ultimate DISCO” uses a solvent that shrinks whole animals and preserves fluorescence for months.

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image: Top Technical Advances 2015

Top Technical Advances 2015

By | December 24, 2015

The Scientist’s choice of major improvements in imaging, optogenetics, single-cell analyses, and CRISPR

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image: Imaging Live Tissue Without Fluorescence

Imaging Live Tissue Without Fluorescence

By | October 30, 2015

Modifying a vibration-based optical technique can capture images of living tissues, researchers show. 

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image: Comprehensive Microbiome Initiatives Proposed

Comprehensive Microbiome Initiatives Proposed

By | October 29, 2015

To unify disparate research groups, scientists call for a new approach to studying the Earth’s microbiome.

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image: Imaging Entire Organisms

Imaging Entire Organisms

By | October 26, 2015

A new microscope allows researchers to watch biological processes at the cellular level in 3-D in living animals. 

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image: The First Neuron Drawings, 1870s

The First Neuron Drawings, 1870s

By | October 1, 2015

Camillo Golgi’s black reaction revealed, for the first time, the fine structures of intact neurons, which he captured with ink and paper.

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image: Watching Live Cells

Watching Live Cells

By | August 28, 2015

An international team brings the new technology of super-resolution imaging to the world of the living.

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image: Fruit-Fly Neurons in Action

Fruit-Fly Neurons in Action

By | August 12, 2015

Researchers visualize the complete nervous system of a Drosophila melanogaster larva at nearly single-neuron resolution.

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image: Scanning for SIV’s Sanctuaries

Scanning for SIV’s Sanctuaries

By | May 1, 2015

Whole-body immunoPET scans of SIV-infected macaques reveal where the replicating virus hides.  

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image: Filming the Nematode Brain

Filming the Nematode Brain

By | January 26, 2015

Researchers record the first whole-brain videos of an unrestrained animal, viewing neural activity as a roundworm moved freely around a Petri dish.

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