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tag vitamin c cell molecular biology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Molecular Biology
The Scientist Staff | Nov 14, 1993 | 2 min read
p.17 A.A. Levin, L.J. Sturzenbecker, S. Kazmer, T. Bosakowski, C. Huselton, G. Allenby, J. Speck, C. Kratzeisen, M. Rosenberger, A. Lovey, J.F. Grippo, "9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRa," Nature, 355:359-61, 1992. Arthur A. Levin and Joseph F. Grippo (Department of Toxicology and Pathology, Hoffmann-La Roche Inc., Nutley, N.J.): "The biologic activities of the all-trans (t) isomer of retinoic acid (RA) are mediated through the binding and activati
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Molecular Biology
The Scientist Staff | Aug 22, 1993 | 2 min read
M. Leid, P. Kastner, R. Lyons, et al., "Purification, cloning and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently," Cell, 68:377-95, 1992. Mark Leid (Oregon State University, Corvallis): "The diverse effects of retinoic acid (RA) on development, cellular growth and differentiation, and homeostasis are mediated by two families of RA receptors that arose independently during evolution and belong to the steroid/thyroid hormone super
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
C. elegans cell lineage, circa 1981
Elie Dolgin | Jun 1, 2008 | 1 min read
Credit: courtesy of John Sulston" /> Credit: courtesy of John Sulston Starting in 1980, John Sulston spent 18 months hunched over a microscope watching Caenorhabditis elegans embryos divide. Together with Bob Horvitz at the Laboratory of Molecular Biology in Cambridge, England, he had already mapped the fate of every cell in the adult worm from the moment the egg hatched, but the embryonic cell line
Cell Biology
The Scientist Staff | Oct 13, 1991 | 2 min read
Cell Biology T. Sollner, G. Griffiths, R. Pfaller, N. Pfanner, W. Neupert, "MOM19, an import receptor for mitochondrial precursor proteins," Cell, 59:1061-70, 1989. Thomas Sollner (University of Munich): "The complex organization of eucaryotic cells into various membrane-bound compartments (organelles) requires a very specific targeting of newly synthesized proteins to their final destinations. All noncytosolic proteins are synthesized as signal-carrying precursors, which are decode
Abstract graphene structures
Synthetic Organelles Let Researchers Control Cell Behavior
Catherine Offord | Nov 1, 2021 | 3 min read
A technique that reversibly bundles tagged cargo into artificial membraneless compartments gives scientists the ability to switch cell processes on and off.

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