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tag histone methylation cell molecular biology evolution genetics genomics

Illustration from the epigenetics and the genome infographic
Infographic: How Epigenetic Marks Can Change the Genome
Katarina Zimmer | Nov 1, 2022 | 2 min read
Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Histone Methylation is Making its Mark
Brendan Maher | Jan 26, 2003 | 6 min read
Data derived from the Science Watch/Hot Papers database and the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. M. Lachner et al., "Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins," Nature, 410:116-20, 2001. (Cited in 202 papers) A.J. Bannister et al., "Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain," Nature, 410:120-4, 2001. (Cited in 2
a microscope image of a rotifer
Bacterial Enzyme Keeps Rotifers’ Transposable Elements in Check
Christie Wilcox, PhD | Mar 3, 2022 | 5 min read
Jumping genes in bdelloid rotifers are tamped down by DNA methylation performed by an enzyme pilfered from bacteria roughly 60 million years ago, a study finds.
Layered visual representation of multiomics
Integrate and Innovate with NGS and Multiomics
The Scientist and Illumina | May 4, 2023 | 6 min read
Researchers across disciplines combine layers of discovery obtained with accessible NGS-based multiomics approaches.
Heritable Histones
Ruth Williams | Sep 18, 2014 | 3 min read
Scientists show how roundworm daughter cells remember the histone modification patterns of their parents.
close-up of X chromosomes
Probing “Selfish” Centromeres Unveils an Evolutionary Arms Race
Michael Lampson, PhD | Apr 3, 2023 | 10 min read
A more complete understanding of nonrandom segregation will shed light on how speciation occurs.

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