cell & molecular biology, immunology

One of the most advanced tuberculosis vaccines has failed to protect infants from getting the disease in a clinical trial, but it may be effective in adults.

Certain immune cells keep adipose tissue in check by helping to define normal and abnormal physiological states.

Inflammatory signals in injured zebrafish brains promote the growth of new neurons.

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role

The Scientist recounts the year’s top science prize winners and top-notch scientists that passed away.

The Nobel Assembly announced today that three researchers in the field of immunology will share the 2011 Prize in Physiology or Medicine.

Nerve signals control T cell responses, helping to explain inflammation and stroke.

Editor's Choice in Immunology

The Nobel Prize winner who discovered the gene that encodes the major histocompatibility complex passes away at age 90.

The president of the University of the Ryukyus in Japan coauthored a paper containing a duplicated figure.

A snapshot of the most highly ranked articles in vaccination and related areas, from Faculty of 1000

It may be time to reconsider an AIDS vaccine which is more human than viral, triggering the immune system in a way that no other vaccine does.

In discovering their shared ancestry, a distantly related animal geneticist and plant pathologist find a common thread in their work on immune receptors.

Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. 

Can tumors—which can originate from, and often resemble, chronically inflamed tissue—be curtailed using familiar anti-inflammatory agents, without their side effects?

A snapshot of the highest-ranked articles from a 30-day period on Faculty of 1000

Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 

A snapshot of the highest-ranked articles from a 30-day period on Faculty of 1000

Watch white blood cells as they scurry along blood vessels and descend upon an injury site.