stem cells

Japanese health officials approve human experiments to treat macular degeneration with a cell therapy derived from induced pluripotent stem cells.

Removing a specific miRNA from stem cells may induce the expression of endogenous retroviruses that enable the cells to form extra-embryonic lineages.

Scientists repurpose an Alzheimer’s drug to enhance the ability of stem cells to repair dental damage in mice.

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

Andrzej Tarkowski’s research laid the groundwork for future advances in cloning, stem cell research, and in vitro fertilization.

Sequencing and gene-editing advances make tracing a cell’s journey throughout development easier than ever.

The Scientist caught up with cardiac stem cell researcher Mark Sussman to get his thoughts on the American Heart Association’s Scientific Sessions meeting.

While studying a rare genetic disease, researchers discovered a signaling pathway linked to the efficiency of reprogramming somatic cells into stem cells.

Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds

After a heart attack, monkeys given induced pluripotent stem cell–derived cardiomyocytes show more regeneration in the organ, but with risks.

Celebrating 30 years and a resurrection

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

Since The Scientist published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.

Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.

Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

Mutations that arise during stem cell division contribute to the development of cancers in a variety of organs, according to a study.

A mouse study shows that the virus has tropism for adult proliferative neural progenitor cells and immature neurons.

The public gets to weigh in before the US government lifts its ban on such research.

A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.

Increasingly sophisticated tissue organoids can model many aspects of disease, but animal studies retain a fundamental role in research, scientists say.